I had a CTD after about an hour of play. SE dump and debug.err files sent to the gc2bugs address. Wasn't doing anything special at the time just whacking the turn button waiting for tech research to complete.
Initial thoughts:
The game is much more playable.
The new tech navigator provides a much nicer way to deal with the tech tree.
The ship-to-ship combat is nice but is only really visible at high zoom. I tend to play large portions of the game with everything zoomed out to the strategic map.
Starbases seem to be fairly incomplete - case in point I built a military starbase with the base defense module and while the detail view said it was there and applied the bonus the main starbase view had a zero for defense.
I haven't had a chance to dig into this yet but I think the ship building process won't let me build ships as nice as the pre-made ones. I ended up using the stock ships more for that reason.
That's it for now. Hopefully I'll have more time to play over the weekend.
Overall a big improvement over beta 2.
