the two that would be most helpful to move around are the quick build list and the transport/ colony population popups.
if you build four or five in one turn, the new ship icon is in the lower right corner, the launch button is in the lower left corner, and the troops window is in the middle of the screen. it's like your doing laps with your mouse, lol. currently playing at 1280x1024 resolution but thinking of upgrading to a 1920x1600 monitor... i could crank up the pointer speed, but the buttons are kind of small targets.
alternatively, it would be great if the orbit/ launch window and the ship info window swapped places, so that launch button was down there right next to the done button.