Played it on Windows 7. No problems
I'm having all kinds of problems. But, not sure what is from bugs and what is from Windows 7. I can't get Impulse to run at all to update the game. Nice of them to get all fancy instead of just putting out a patch. I've heard from someone from Stardock on this, but it didn't fix the problem, waiting to hear back.
I can play very few games. If I choose anything other than normal tech start (i.e. accelerated start), or anything other than a small galaxy it crashes. From seeing other posts I don't know if even updating the game would fix these problems. Sounds like it's just buggy as all hell.
Tempted to load Windows XP on another partition to see if I can update and play the game like that.