As near as I can tell from looking at the stats, there's never a reason to maintain standard research buildings once Neutrality Learning Centers have been researched; they are better in every way. Why, then, do they not replace other research buildings on the list and, consequently, never get chosen for upgrades by the colony control functions? It's frustrating and time consuming in the mid- to end-game to have to go colony to colony and manually cancel research upgrades, replacing them with learning centers.