We've just sent you a copy of your serial number for GC2 to your email address.

Take the serial number, go into your c:\stardock\totalgaming\galciv2 folder (of wherever it was installed), and locate a file called "sig.bin". Delete this file, and run GalCiv2.exe. You'll be prompted to activate your copy...do this by entering your email address and the game's serial number.

Hope this gets the game running for you! If not, contact support@stardock.com with your problem...they may be able to help you better.