It won't delay (by much, if any) the release of the next core TES game. As for it going F2P, as many of us expect, I'm not sure it'll impact too much on their financials. The game has been a long time developing and with its graphics and engine, etc., it's obvious that it wasn't being fully developed that entire time. So man-hours and money were spread out.
Add to that Bethesda's upcoming releases of extra IP's (Wolfenstein and The Evil Within), plus whatever else Zenimax has and/or does, and if there is significant financial loss it will likely be mitigated and spread throughout its other holdings, etc.
That's not taking into consideration what they've already earned through pre-orders nor what they'll receive with regular purchases and whomever pays the monthly fees until it crashes.
Hell, they could have already written off the developing costs and whatever by spreading it already throughout Zenimax holdings. Everything to date could be wrangled as pure profit. Which would suck.
Fallout 4...I would love for it to have a multiplayer element. But for small parties, 2-4 thereabouts. Yet at the same time I'd rather have it remain single-player.