I disagree, been playing immense on Win XP and now Win 7 64-bit with no issues or slow down.
My specs of my machine are a Geforce 470 GTX, Q6600 running at 3.2 gig, 8 gigs of RAM (old DDR2 machine) an intel x-25M 80GB SSD as OS drive (game is on on a 2 TB WD black 7200 rpm drive though), creative labs x-fi for sound
Had this machine for about 3 years now so not exactly cutting edge.
All textures at max, all details on max resolution = 1680 x 1050 on my TFT.
Perfectly playable with no slow down. I know a lot of processors and some gfx cards have superceeded my machine