DNF can't ever come out any more. Not because it was cancelled or anything, but because it would kill the meme. We wouldn't be able to say "oh, that game's gone the way of Duke Nukem Forever" anymore. A new game would have to be found to replace it. DNF has become synonomous with vaporware, you can't go messing with that!
More seriously though, no, I don't really care. After all this time, I doubt it can live up to 14 years worth of expectations. If it is real, I feel like at this point it would be little more than a money grab. People will buy just because it is the game that was never going to come out, not because it is any good.