I'm not a huge gamer, quite often going the better part of a year between playing anything. There are two franchises that I make exceptions for-
1) Turn based strategy, the last good one being Gal Civ series before that the classics like MOO and Civilization
2) Fallout- never really got into RPG's but for some reason the fallout franchise I dig bigtime!
This weekend I bought fallout 3 and it is AMAZING.
If you have a PC that can run it or an Xbox-360, I highly recommend it. If nothing else it's worth it since you can make your own weapons, like a bazooka-type thing with a vacuum cleaner and other assorted parts, shooting random junk you find like tin cans or pencils
Or, if you find an old lunch box, some bottlecaps and a cherry bomb you can make an improvised landmine, and so on.
And, the bonus of it all is that you're playing in a post-apocalyptic wasteland that you really don't get to see too often in a lot of gaming environments.
Fallout 3- more than worth it's weight in gold (or pixelated gold, whatever)