What's extra-evil about EA is that the most recent patch for Spore actually addresses some of the space-stage stagnation, but you can only get it with the EA Download Manager and a legitmate copy.
Funny how anyone who playtested for EA would've noticed that Space is unplayable in the way it went gold, then very shortly after a patch that makes it playable is released, but only through thier Download Manager.
Curious, if you ask me. 
Back to topics:
Empire: Total War - A Total War game set during the colonization of America, including the Revolutionary War? With full naval combat and co-op online campaigns? This game was sold to me when it was conceptualized. 
Left4Dead - Got a whole group to help me kill some zombies when this drops.
Diablo 3 - Nuff' said.
Starcraft 2 - Again, nuff' said.
I may be the odd man out in that I'm not particularly stoked for Demigod - I played some DOTA in WC3 and didn't like the fact that it seemed to be "level up on hordes of NPCs so you can fight another player."
If it has a players versus NPC hordes mode I'll be more interested.