Alright, I have had this bug a few times, so I'm guessing that it has already been reported, but it is so bad that I'm going to post it anyway. Unless I say otherwise, all these bugs came up with the latest patch.
Sometimes, when I take over a planet, the happyness and influence variables get messed up. My influence will cover the whole galaxy(which is good for me^_^), but my races happyness will go down to 1%...which is very bad. One time when this happened my people revolted against me and I had to load the game. Oh, and I think that all the other race's happyness goes down to 1% as well, because one time when this happened I noticed that all the computer's planets had skull and crossbones symbols. These problems only happen after I take over a planet, and it tends to last two turns. It has happened about 5 times I think, and considering that I have only played 6 or 7 games, that is a pretty high rate.
I have also had a crash on the loading screen as I started up my game, though I have no idea what caused it or how to reproduce it.
This one happened on my game when it was unpatched, so you might have fixed it for all I know: once I was trying to save a ship I had created, but I kept on clicking the button, but nothing happened, so I exited the shipbuilder to see if making the ship again would work, but then a bunch of messages popped up saying something something about saving my ship, and then the game crashed as I clicked though them.