Hi!
In my current DA 1.50.72 fastest-tech maso game I for the first time allowed my planets to build "ultimate" production and research buildings: Neutrality Learning Centers and Industrial Sectors. Those two combined changed my financial state dramatically, and for the worse. Let me explain that a bit more.

Im most my games I build my planets by a simple rule of thumb: 1/4 of every kind of buildings: 1/4 factories, 1/4 labs, 1/4 banks and 1/4 for other purposes (colony center, 1 morale, 1 farm, starport, specialization, "wonders"...). In DA with nerfed factories I sligtly increased amount of them to ~30%. My usual spending sliders settings are 1%/49%/50%, and in late mid game, when my core ~20 planets achieve maturity (all tiles used with the latest kind of buildings, but not NLCs and ISs), I'm usually flowing in money. At that time I usually have in possession at least one of each kind of galactic resources, ofc. most of them fully mined.

My current game went about the same way, but then I decided to build NLCs first, and after them also the ISs. Since both cost a lot of money (=time to build) I decreased my research slider from 50% to 30%. The first effect I noticed when first NLCs on bonus tiles came on-line was a drop in income: all of a sudden I couldn't spend money for spies. Playing as a Kryn that sounds silly, but that was just a consequence of moving from Reseach Academies with 14 TP output to NLCs with 22. To alleviate that I had to lower my research slider for another 5%, but that was just a temporary solution. Since more and more more NLS were built, they required more and more money to feed ther enormous output. So I increased taxes from 69% to 79%. That helped, but when my planets started producing ISs, my financial situation again went to worse. Those ISs cost lots of money to maintain and require 20% more money to feed their production. Just from five HWs I currentely possess (that have the usuall infrastructure: manuf. capital, Quantum power plant and ~5 ISs and one-two starbases for support) I get so much production I can not afford to fincance it.

Here's my current situation:
- I'm running taxes at 71% to allow newly conquered planets to grow at 100% approval, producing 8300BC from taxes,
- I have Federation as government,
- my econ ability is at 108%, morale 174% and research 133%,
- 3 turns ago I had an econ treaty worth 200BC with Altarians, the third strongest econ,
- all my older planets have Stock Markets, on most newly conquered I'm building financial buildings exclusively, even converting other buildings into it,
- all my trade routes (11) are active, bringing measly 340BC, with potential of ~800 (my financial capital brings 340, average planet at 9B pop ~200),
- my empire produces 370BC from turism,
- my espionage spending is turned off, my research is all-time high despite its slider is at 21%, several production-heavy planets are turned off (nothing in military queue), but
- I'm still barely runing positive income, as that dozen of newly conquered planets with 1-2B pop costs me ~40BC to have each.

Solution: win ASAP. In the mean time I'm:
- growing pop at 100% approval on most planets to make those new planets pay for themself ASAP,
- converting some ISs into Stock markets,
- converting other buildings on conquered planets into Banks/Stock Markets/Trade centers, covering empty tiles with Trade Centers, and
- researching the latest morale tech to build the only one morale "wonder" I don't have yet, to increase taxes back to 79%.

Conclusion
My "1/4" model does not allow me tu fully utilize those ultimate buildings. In future games I'll need much more econ buildings before I can afford too build NLCs and ISs. The best approach will probably be to
- build lately-gained planets into econ planets (most econ buildings), and
- on "old" planets to convert one of existing research and one production buildig on most planets to Stock Markets, before actually building there NLCs and ISs.

BR, Iztok