I do the same thing every game: Start with sliders on military 100, get some colony ships out to make the initial rush. Then shut military down and go social/research 50-50. My first seven research projects are the same every time: communications, universal translator, diplomacy, medical, basic environment, industrial, interstellar refining.
Then I start varying it up but if grav accel have not already been built by someone, I go artifical grav then controlled grav to start work on that. I then check to see if other races have nano-metal composition and advanced trade. I then get these as quick as I can and start building tri-steel and galactic stock exchange. then things usually diverge for me depending on if someone I'll likely be at war with is getting close to battleship(intersteller tactics and warp drive). If so, I get tactics and warp drive. If not, I go intersteller business, cultural trade, intersteller marketing, intersteller capitalism to open those wonders and the nice stock market improvement. On crippling and below this can be pulled off. What I do on crippling and below is build habitat, manufacturing center, and fusion power plant then start building the wonders/TGs tossing in an entertainment network when needed.
On maso, after hitting intersteller refining (and even before that on maps bigger than small, wonders/TGs are already being built by the AI so things tend to fall apart for my tech plan after that. On maso, I try to stay a step behind ship wise if possible. That is, I want to have frigates by the time the AI gets battleships. If you can stay close and weather the storm and can survive to get dreads, it's over (assuming some AI doesn't already have overlords).
~SDC~