I am having various video issues with GC2. Text and other Gui boxes are not rendered, overlayed incorrectly or missing information. A sample is visible on the address below. I run a Fujitsu 5010 with XP.
http://img6.imageshack.us/img6/7119/gc2taterranalliance1236.jpg
UPDATE
I have uinstalled and reinstalled galciv to no avail. It seems worse with hardware T&L button deselected (however it is almost equally unplayable late game). Here is another problem picture from DA where the menu disappears. It will do this without fail if I have my cursor over the turn button.
http://img26.imageshack.us/img26/5448/gc2daterranalliance1236.jpg