New TA Yor game, very early in the colony rush. My Space Miner finishes building the three mining bases closest to my home planet, then it scoots off for the next closest asteroid field. However, as it happened, the next field was directly opposite the home planet, directly in the pathway. When it started heading there, I could see the autopilot path bending around the planet. But it didn't do that; it went into orbit around Iconia instead.
It took a few turns to notice that ("Hey, who stole my Space Miner?!") since it just disappeared from the galaxy map. I had it on automated mining, I wasn't manually clicking a path. Launching it from orbit started it towards the new asteroid field. Looks like the pathfinding bugs aren't completely ironed out.