I have noticed that about 2 hours into every game I play, galactic civilizations 2 crashes. I happened to catch windows saying there was a lack of page file memory one time when I alt tabbed before it crashed. I'm runnin windows XP, the first version of galactic civlizations (retail, i'm not big on updating things but if this is fixed in a patch I guess I will have to), 512 mb ram, and I guess if there is any other information that you need I can supply it.
When it crashes, the game shuts down instantly, and I get the standard windows popup with an error report and it asks if I want to submit it to microsoft.